Synthesis of Chiral Heteronucleotide ONA Sequences by a Fmoc/Boc-Based Submonomeric Strategy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Molecular Medicine,Biochemistry,Bioengineering,Analytical Chemistry
Link
http://link.springer.com/content/pdf/10.1007/s10989-009-9181-4.pdf
Reference16 articles.
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2. Corradini R, Sforza S, Tedeschi T, Marchelli R (2007) Chirality as a tool in nucleic acid recognition: principles and relevance in biotechnology and in medicinal chemistry. Chirality 19:269–294
3. Dueholm LK, Egholm M, Behrens C, Christensen L, Hansen FH, Vulpius T, Petersen HK, Berg HR, Nielsen PE, Buchardt O (1994) Synthesis of peptide nucleic acid monomers containing the four natural nucleobases: thymine, cytosine, adenine, and guanine and their oligomerization. J Org Chem 59:5767–5773
4. Ganesh NK, Nielsen PE (2000) Peptide nucleic acids analogs and derivatives. Curr Org Chem 4:931–935
5. Krotz A, Cole D, Ravikumar V (1999) Synthesis of an antisense oligonucleotide targeted against C-raf kinase: efficient oligonucleotide synthesis without chlorinated solvents. Bioorg Med Chem 7:435–439
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