HIF-1α is an important regulator of IL-8 expression in human bone marrow stromal cells under hypoxic microenvironment
Author:
Funder
the National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Plant Science,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00709-023-01920-z.pdf
Reference34 articles.
1. Abdul-Aziz AM, Shafat MS, Mehta TK, Palma FD, Lawes MJ, Rushworth SA et al (2016) MIF-induced stromal PKCβ/IL8 is essential in human acute myeloid leukemia. Cancer Res 77:303–311. https://doi.org/10.1158/0008-5472.CAN-16-1095
2. Abdul-Aziz AM, Sun Y, Hellmich C, Marlein CR, Mistry J, Forde E et al (2019) Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment. Blood 133:446–456. https://doi.org/10.1182/blood-2018-04-845420
3. Albadari N, Deng S, Li W (2019) The transcriptional factors HIF-1 and HIF-2 and their novel inhibitors in cancer therapy. Expert Opin Drug Discov 14:667–682. https://doi.org/10.1080/17460441.2019.1613370
4. Antonelli A, Scarpa ES, Magnani M (2021) Human red blood cells modulate cytokine expression in monocytes/macrophages under anoxic conditions. Front Physiol 12:632682. https://doi.org/10.3389/fphys.2021.632682
5. Bruno S, Mancini M, De Santis S, Monaldi C, Cavo M, Soverini S (2021) The role of hypoxic bone marrow microenvironment in acute myeloid leukemia and future therapeutic opportunities. Int J Mol Sci 22. https://doi.org/10.3390/ijms22136857
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