Synthesis of diacetoxy acetal derivatives of santonin and their enhancing effects on HL-60 leukemia cell differentiation

Author:

Kim Seung Hyun,Chung Sun Young,Kim Tae Sung,Choi Bo Gil

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Reference16 articles.

1. Ando, M., Wada, T., Kusaka, H., Takase, K., Hirata, N., and Yanagi, Y., Studies on the synthesis of sesquiterpene lactones 10. Improved synthesis of (+)-tuberiferin and the related alpha-methylene gamma-lactones and their biological activities.J. Org. Chem., 52, 4782–4786 (1987).

2. Beere, H. M. and Hickman, J. A., Differentiation: a suitable strategy for cancer chemotherapy.Anti-Cancer Drug Design, 8, 299–322 (1993).

3. Breitman, T. R., Selonick, S. E., and Collins, S. J., Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.Proc. Natl. Acad. Sci., U.S.A., 77, 2936–2940 (1980).

4. Collins, S. J., Ruscetti, F. W., Gallagher, R. E., and Gallo, R. C., Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide.J. Exp. Med., 149, 969–974 (1979).

5. Hall, I. H., Williams, W. L. Jr., Grippo, A. A., Lee, K. H., Holbrook, D. J., and Chaney, S. G., Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones.Anticancer Res., 8, 33–42 (1988).

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