Site specific polarization transfer from a hyperpolarized ligand of dihydrofolate reductase
Author:
Funder
National Institute of General Medical Sciences
Welch Foundation
Publisher
Springer Science and Business Media LLC
Subject
Spectroscopy,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s10858-016-0037-x.pdf
Reference33 articles.
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2. Ardenkjær-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, Servin R, Thaning M, Golman K (2003) Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR. Proc Natl Acad Sci USA 100:10158–10163
3. Bowen S, Hilty C (2010) Rapid sample injection for hyperpolarized NMR spectroscopy. Phys Chem Chem Phys 12:5766–5770
4. Breeze AL (2000) Isotope-filtered NMR methods for the study of biomolecular structure and interactions. Prog Nucl Magn Reson Spectrosc 36:323–372
5. Bystroff C, Kraut J (1991) Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding. Biochemistry 30:2227–2239
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