Pain Management of Patients with Substance Abuse in the Ambulatory Setting

Author:

Vadivelu Nalini,Kai Alice M.,Kodumudi Vijay,Zhu Richard,Hines Roberta

Publisher

Springer Science and Business Media LLC

Subject

Anesthesiology and Pain Medicine,Clinical Neurology,General Medicine

Reference53 articles.

1. • Huffman KL et al. Nonopioid substance use disorders and opioid dose predict therapeutic opioid addiction. J Pain. 2015;16(2):126–34. This paper showed that a high opioid dosage requirement and the presence of substance abuse are associated with a higher risk of opioid addiction. This relates highly to our review because surgical patients are exactly the demographic who will have increased dose requirements due to postoperative pain, and those patients who are coming to surgery with a history of substance use are especially susceptible.

2. Hall AJ et al. Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA. 2008;300(22):2613–20.

3. Paulozzi LJ, Budnitz DS, Xi Y. Increasing deaths from opioid analgesics in the United States. Pharmacoepidemiol Drug Saf. 2006;15(9):618–27.

4. • Dart RC et al. Trends in opioid analgesic abuse and mortality in the United States. N Engl J Med. 2015;372(3):241–8. Although clinically, an increasing trend in opioid use and substance use in our patients is obvious, it is hard to demonstrate unequivocally in data due to the difficulty of collecting such a large database of information over time, especially for current data. This paper summarizes these trends over the last 15 years, in particular, giving numbers for the large increase in opioid prescriptions since 2002 and the increase in opioid diversion and abuse since 2002.

5. Soyka M. New developments in the management of opioid dependence: focus on sublingual buprenorphine-naloxone. Subst Abuse Rehabil. 2015;6:1–14.

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