Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus-Reference-Cited by-同舟云学术

Generation of antibody- and B cell-deficient pigs by targeted disruption of the J-region gene segment of the heavy chain locus

Published:2010-09-26 Issue:3 Volume:20 Page:625-641
ISSN:0962-8819
Container-title:Transgenic Research
language:en
Short-container-title:Transgenic Res

Author:

Mendicino M.,Ramsoondar J.,Phelps C.,Vaught T.,Ball S.,LeRoith T.,Monahan J.,Chen S.,Dandro A.,Boone J.,Jobst P.,Vance A.,Wertz N.,Bergman Z.,Sun X-Z.,Polejaeva I.,Butler J.,Dai Y.,Ayares D.,Wells K.

Publisher

Springer Science and Business Media LLC

Subject

Agronomy and Crop Science,Genetics,Animal Science and Zoology,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11248-010-9444-z.pdf

Reference56 articles.

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3. Butler JE, Sinkora M (2007) The isolator piglet: a model for studying the development of adaptive immunity. Immunol Res 39:33–51

4. Butler JE, Sun J, Navarro P (1996) The swine Ig heavy chain locus has a single JH and no identifiable IgD. Int Immunol 8:1897–1904

5. Butler JE, Sun J, Weber P, Navarro P, Francis D (2000) Antibody repertoire development in fetal and newborn piglets, III. Colonization of the gastrointestinal tract selectively diversifies the preimmune repertoire in mucosal lymphoid tissues. Immunology 100:119–130

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