A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1-Reference-Cited by-同舟云学术

A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1

Published:2008-11-26 Issue:2 Volume:18 Page:261-279
ISSN:0962-8819
Container-title:Transgenic Research
language:en
Short-container-title:Transgenic Res

Author:

Mangerich Aswin,Scherthan Harry,Diefenbach Jörg,Kloz Ulrich,van der Hoeven Franciscus,Beneke Sascha,Bürkle Alexander

Publisher

Springer Science and Business Media LLC

Subject

Agronomy and Crop Science,Genetics,Animal Science and Zoology,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11248-008-9228-x.pdf

Reference60 articles.

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2. Adair GM, Nairn RS, Wilson JH et al (1990) Targeted gene replacement at the endogenous APRT locus in CHO cells. Somat Cell Mol Genet 16:437–441. doi: 10.1007/BF01233193

3. Adair GM, Scheerer JB, Brotherman A et al (1998) Targeted recombination at the Chinese hamster APRT locus using insertion versus replacement vectors. Somat Cell Mol Genet 24:91–105. doi: 10.1023/B:SCAM.0000007112.62928.d8

4. Aratani Y, Okazaki R, Koyama H (1992) End extension repair of introduced targeting vectors mediated by homologous recombination in mammalian cells. Nucleic Acids Res 20:4795–4801. doi: 10.1093/nar/20.18.4795

5. Ayares D, Chekuri L, Song KY et al (1986) Sequence homology requirements for intermolecular recombination in mammalian cells. Proc Natl Acad Sci USA 83:5199–5203. doi: 10.1073/pnas.83.14.5199

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