A germline transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon

Author:

Tomita Masahiro,Hino Rika,Ogawa Shingo,Iizuka Masashi,Adachi Takahiro,Shimizu Katsuhiko,Sotoshiro Hisaya,Yoshizato Katsutoshi

Publisher

Springer Science and Business Media LLC

Subject

Agronomy and Crop Science,Genetics,Animal Science and Zoology,Biotechnology

Reference34 articles.

1. Adachi T, Tomita M, Yoshizato K (2005) Synthesis of prolyl 4-hydroxylase alpha subunit and type IV collagen in hemocytic granular cells of silkworm, Bombyx mori: involvement of type IV collagen in self-defense reaction and metamorphosis. Matrix Biol 24:136–154

2. Adachi T, Tomita M, Shimizu K, Ogawa S, Yoshizato K (2006) Generation of hybrid transgenic silkworms that express Bombyx mori prolyl-hydroxylase alpha-subunits and human collagens in posterior silk glands: Production of cocoons that contained collagens with hydroxylated proline residues. J Biotechnol (in press) DOI 10.1016/j.jbiotec.2006.04.035

3. Bando H, Hayakawa T, Kawasaki M, Matsuyama T, Yamada Y, Kojima K, Yamagishi J (1999) The principal transregulatory protein of nuclear polyhedrosis virus, IE1: a functional analysis of BmNPV IE1. RIKEN Rev 22:26–29

4. Cochran MA, Faulkner P (1983) Location of homologous DNA sequences interspersed at five regions in the baculovirus AcMNPV genome. J Virol 45:961–970

5. Carson DD, Summers MD, Guarino LA (1991) Transient expression of the Autographa californica nuclear polyhedrosis virus immediate-early gene, IE-N, is regulated by three viral elements. J Virol 65:945–951

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