The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia

Author:

Dallmann R.12,Weyermann P.1,Anklin C.1,Boroff M.1,Bray-French K.1,Cardel B.1,Courdier-Fruh I.1,Deppe H.1,Dubach-Powell J.1,Erb M.1,Haefeli R. H.1,Henneböhle M.1,Herzner H.1,Hufschmid M.1,Marks D. L.3,Nordhoff S.1,Papp M.4,Rummey C.1,Santos G.1,Schärer F.1,Siendt H.1,Soeberdt M.1,Sumanovski L. T.1,Terinek M.1,Mondadori C.1,Güven N.1,Feurer A.1

Affiliation:

1. Santhera Pharmaceuticals (Switzerland) Ltd.; Hammerstr. 49 4410 Liestal

2. Institute of Pharmacology and Toxicology; University of Zurich; Winterthurerstr. 190 8057 Zurich

3. Department of Pediatric Endocrinology, Vollum Institute; Oregon Health Sciences University; Portland

4. Institute of Pharmacology; Polish Academy of Sciences; Krakow

Publisher

Wiley

Subject

Physiology (medical),Orthopedics and Sports Medicine

Reference60 articles.

1. Cachexia: a new definition;Evans;Clin Nutr,2008

2. The use of melanocortin antagonists in cachexia of chronic disease;Scarlett;Expert Opin Investig Drugs,2005

3. Cachexia in cancer patients;Tisdale;Nat Rev Cancer,2002

4. Analysis of the energy balance in lung cancer patients;Staal-van Brekel;Cancer Res,1994

5. Therapy insight: cancer anorexia-cachexia syndrome-when all you can eat is yourself;Laviano;Nat Clin Pract Oncol,2005

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