Risk Stratification in Lung Resection

Author:

Salati Michele,Brunelli Alessandro

Publisher

Springer Science and Business Media LLC

Subject

Surgery

Reference43 articles.

1. •• Brunelli A, Kim AW, Berger KI, Addrizzo-Harris DJ. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery. Chest 2013;143:166S–190S. The Authors performed a rigorous review of the medical literature proposing a list of evidence based recommendations and an exhaustive algorithm for the preoperative physiologic assessment in patients candidates to lung resection for NSCLC. Once performed the cardiac and spirometric evaluations with the estimation of the FEV1 and DLCO predictive postoperative values, the final risk stratification should be obtained considering the VO2max measured at the cardiopulmonary exercise test.

2. Brunelli A, Charloux A, Bolliger CT, Rocco G, Sculier JP, Varela G, Licker M, Ferguson MK, Faivre-Finn C, Huber RM, Clini EM, Win T, De Ruysscher D, European Respiratory Society and European Society of Thoracic Surgeons joint task force on fitness for radical therapy. ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J. 2009;34:17–41.

3. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, Sugarbaker DJ, Donaldson MC, Poss R, Ho KK, Ludwig LE, Pedan A, Goldman L. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100:1043–9.

4. Brunelli A, Varela G, Salati M, Jimenez MF, Pompili C, Novoa N, Sabbatini A. Recalibration of the revised cardiac risk index in lung resection candidates. Ann Thorac Surg. 2010;90:199–203.

5. • Brunelli A, Cassivi SD, Fibla J, Halgren LA, Wigle DA, Allen MS, Nichols FC, Shen KR, Deschamps C. External validation of the recalibrated thoracic revised cardiac risk index for predicting the risk of major cardiac complications after lung resection. Ann Thorac Surg. 2011;92:445–448. The Authors validated the use of a multiparametric cardiac risk index (ThRCRI) developed to assess the risk of adverse cardiac events after lung resection. They found, in a cohort of 2,621 patients, a progressive increase of observed complication rate in line with the class of risk assigned to the patients (class A: cardiac complication rate 0.9%, B: 4.2%, C: 8%, D: 18%). This study confirm the reliability of the ThRCRI.

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