Isolation and characterization of two acaricidal compounds from Calpurnia aurea subsp. aurea (Fabaceae) leaf extract-Reference-Cited by-同舟云学术

Isolation and characterization of two acaricidal compounds from Calpurnia aurea subsp. aurea (Fabaceae) leaf extract

Published:2018-05-30 Issue:3 Volume:75 Page:345-354
ISSN:0168-8162
Container-title:Experimental and Applied Acarology
language:en
Short-container-title:Exp Appl Acarol

Author:

Adenubi Olubukola T.^ORCID,Ali Abdalla Muna,Ahmed Aroke S.,Njoya Emmanuel M.,McGaw Lyndy J.,Eloff Jacobus N.,Naidoo Vinny

Publisher

Springer Science and Business Media LLC

Subject

Insect Science,Ecology,General Medicine

Link

http://link.springer.com/article/10.1007/s10493-018-0269-4/fulltext.html

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1. Antidermatophytic quinolizidine alkaloids from Calpurnia aurea subsp. aurea (Aiton) Benth;Fitoterapia;2023-12

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5. From the leaves and bark of the Kenyan medicinal plant Calpurnea aurea subsp. aurea, four previously undescribed quinolizidine alkaloids namely, 2β-Methoxy-13α-o-(2’-pyrrolylcarbonyl) virgiline, 2α-Methoxy-13β-o-(2’-pyrrolylcarbonyl) virgiline, 3α-o-Angelate-2β-hydroxy-13α-o-(2’-pyrrolylcarbonyl) virgiline, -2, 3-Deydro-virgiline were isolated together with four known ones. Structural elucidation of the compounds was based on 1D and 2D NMR spectroscopy and mass spectrometry. Their relative configurations were determined by NOESY correlations and literature. The quinolizidine alkaloids were tested against Trichophyton rubrum, Trichophyton interdigitale, Trichophyton benhamiae, Microsporum canis and Nannizzia gypsea, common causative agents of most of the Tinea infections in human. All the isolated quinolizidine alkaloids exhibited antidermatophytic activity with MIC ranging from 37.5;2023