Off-target genome editing: A new discipline of gene science and a new class of medicine
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Cell Biology,Toxicology
Link
http://link.springer.com/content/pdf/10.1007/s10565-019-09475-7.pdf
Reference19 articles.
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2. Fang H, Wang W. Could CRISPR be the solution for gene editing’s Gordian knot? Cell Biol Toxicol. 2016;32(6):465–7. https://doi.org/10.1007/s10565-016-9359-4 .
3. Gupta RK, Abdul-Jawad S, McCoy LE, Mok HP, Peppa D, Salgado M, et al. HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation. Nature. 2019. https://doi.org/10.1038/s41586-019-1027-4 .
4. Jin S, Zong Y, Gao Q, Zhu Z, Wang Y, Qin P, et al. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science. 2019. https://doi.org/10.1126/science.aaw7166 .
5. Kim D, Kim D, Lee G, Cho SI, Kim JS. RNA-guided adenine base editors. Genome-wide target specificity of CRISPR. Nature Biotechnol. 2019;37:430–5. https://doi.org/10.1038/s41587-019-0050-1 .
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