3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Cell Biology,Toxicology
Link
https://link.springer.com/content/pdf/10.1007/s10565-021-09612-1.pdf
Reference71 articles.
1. Arlt VM. 3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence. Mutagenesis. 2005;20(6):399–410. https://doi.org/10.1093/mutage/gei057.
2. Arlt VM, Bieler CA, Mier W, Wiessler M, Schmeiser HH. DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling. Int J Cancer. 2001;93(3):450–4.
3. Arlt VM, Gingerich J, Schmeiser HH, Phillips DH, Douglas GR, White PA. Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in MutaMouse and lung epithelial cells derived from MutaMouse. Mutagenesis. 2008;23(6):483–90. https://doi.org/10.1093/mutage/gen037.
4. Arlt VM, Stiborova M, Henderson CJ, Osborne MR, Bieler CA, Frei E, et al. Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols. Cancer Res. 2005;65(7):2644–52. https://doi.org/10.1158/0008-5472.CAN-04-3544.
5. Bauer AK, Velmurugan K, Xiong KN, Alexander CM, Xiong J, Brooks R. Epiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis model. Mol Carcinog. 2017;56(1):94–105. https://doi.org/10.1002/mc.22475.
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