Hirudin ameliorates diabetic nephropathy by inhibiting Gsdmd-mediated pyroptosis-Reference-Cited by-同舟云学术

Hirudin ameliorates diabetic nephropathy by inhibiting Gsdmd-mediated pyroptosis

Published:2021-07-02 Issue: Volume: Page:
ISSN:0742-2091
Container-title:Cell Biology and Toxicology
language:en
Short-container-title:Cell Biol Toxicol

Author:

Han Jiarui,Zuo Zhenkui,Shi Xiujie,Zhang Yage,Peng Zining,Xing Yufeng,Pang Xinxin

Funder

the Henan Province Science and technology research project

Henan Province special key project of traditional Chinese medicine scientific research

Henan Province top-notch personnel training project of traditional Chinese medicine; national backbone personnel training project of traditional Chinese medicine innovation.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Cell Biology,Toxicology

Link

https://link.springer.com/content/pdf/10.1007/s10565-021-09622-z.pdf

Reference24 articles.

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2. Breggia AC, Himmelfarb J. Primary mouse renal tubular epithelial cells have variable injury tolerance to ischemic and chemical mediators of oxidative stress. Oxid Med Cell Longev. 2008;1:33–8.

3. Cheng Q, Pan J, Zhou ZL, Yin F, Xie HY, Chen PP, Li JY, Zheng PQ, Zhou L, Zhang W, Liu J, Lu LM. Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy. Acta Pharmacol Sin. 2021;42:954–63.

4. Fischer KG. Hirudin in renal insufficiency. Semin Thromb Hemost. 2002;28:467–82.

5. Han J, Pang X, Zhang Y, Peng Z, Shi X, Xing Y. Hirudin protects against kidney damage in streptozotocin-induced diabetic nephropathy rats by inhibiting inflammation via P38 MAPK/NF-κB pathway. Drug Des Devel Ther. 2020;14:3223–34.

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