Abstract
Abstract
Purpose
In this systematic review, we included randomized controlled trials from 2004 to 2021 to determine the effect of individual dietary counseling for patients with head and neck cancer, specifically, nutritional outcome, morbidity, and quality of life (QOL), during and after chemo- and chemoradiotherapy.
Methods
In October 2023, a systematic search was conducted searching five electronic databases (Embase, Cochrane, PsychInfo, CINAHL, and Medline) to find studies concerning the use and effectiveness of intensive nutritional care on head and neck cancer patients.
Results
From all 2565 search results, 6 studies with 685 head and neck cancer patients were included in this systematic review. The patients were treated with radiotherapy or radiochemotherapy. The therapy concepts include intensive nutritional support from a dietician. Outcomes were nutritional status, body composition, quality of life, and adverse effect. All studies had low quality, high risk of bias, and reported heterogeneous results: some studies reported significant improved nutrition status, body composition and quality of life, while other studies did not find any changes concerning these endpoints.
Conclusion
Due to the very heterogeneous results and methodical limitations of the included studies, a clear statement regarding the effectiveness of intensive nutritional therapy of head and neck cancer patients is not possible. Further well-planned studies are needed.
Funder
Deutsche Krebshilfe
Universitätsklinikum Jena
Publisher
Springer Science and Business Media LLC
Reference25 articles.
1. Global Cancer Observatory. International Agency for Research on Cancer. World Health Organization. Available at: https://gco.iarc.fr/. Accessed 6 June 2021.
2. Jatoi A, Loprinzi C (2014) The role of parenteral and enteral/oral nutritional support in patients with cancer In: Hesketh P, O'Lipman T (eds). UpToDate. UpToDate Waltham MA. https://www.medilib.ir/uptodate/show/2830. Accessed 12 June 2021.
3. Couch M, Lai V, Cannon T, Guttridge D, Zanation A, George J, Hayes DN, Zeisel S, Shores C (2007) Cancer cachexia syndrome in head and neck cancer patients: part I. diagnosis, impact on quality of life and survival, and treatment. Head Neck 29:401–411. https://doi.org/10.1002/hed.20447
4. Farhangfar A, Makarewicz M, Ghosh S, Jha N, Scrimger R, Gramlich L, Baracos V (2014) Nutrition impact symptoms in a population cohort of head and neck cancer patients: multivariate regression analysis of symptoms on oral intake, weight loss and survival. Oral Oncol 50:877–883. https://doi.org/10.1016/j.oraloncology.2014.06.009
5. Langius JA, Van Dijk AM, Doornaert P, Kruizenga HM, Langendijk JA, Leemans CR, Wejis PJM, Verdonck-de Leeuw IM (2013) More than 10% weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life. Nutr Cancer 65:76–83. https://doi.org/10.1080/01635581.2013.741749
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