A role for ceftazidime/avibactam combination therapy: the question may still be on the table

Author:

Volpicelli LorenzoORCID,Oliva AlessandraORCID

Publisher

Springer Science and Business Media LLC

Reference5 articles.

1. Hsu W, Chuang MH, Tsai WW, Lai CC, Lai HY, Tang HJ. Ceftazidime-Avibactam combination therapy versus monotherapy for treating carbapenem-resistant gram-negative infection: a systemic review and meta-analysis. Infect Published Online May. 2024;13. https://doi.org/10.1007/s15010-024-02277-y.

2. Tumbarello M, Raffaelli F, Giannella M, et al. Ceftazidime-Avibactam Use for Klebsiella pneumoniae carbapenemase-producing K. pneumoniae infections: a Retrospective Observational Multicenter Study. Clin Infect Dis. 2021;73(9):1664–76. https://doi.org/10.1093/cid/ciab176.

3. Paul M, Carrara E, Retamar P, et al. European Society of Clinical Microbiology and Infectious diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine). Clin Microbiol Infect. 2022;28(4):521–47. https://doi.org/10.1016/j.cmi.2021.11.025.

4. Oliva A, Volpicelli L, Di Bari S, et al. Effect of ceftazidime/avibactam plus fosfomycin combination on 30 day mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae: results from a multicentre retrospective study. JAC Antimicrob Resist. 2022;4(6):dlac121. https://doi.org/10.1093/jacamr/dlac121. Published 2022 Dec 7.

5. Shields RK, Nguyen MH, Chen L, Press EG, Kreiswirth BN, Clancy CJ. Pneumonia and renal replacement therapy are risk factors for Ceftazidime-Avibactam treatment failures and resistance among patients with Carbapenem-Resistant Enterobacteriaceae infections. Antimicrob Agents Chemother. 2018;62(5):e02497–17. https://doi.org/10.1128/AAC.02497-17. Published 2018 Apr 26.

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