Significance of chronic marked hyperglycemia on FDG-PET: is it really problematic for clinical oncologic imaging?

Author:

Hara Tadashi,Higashi Tatsuya,Nakamoto Yuji,Suga Tsuyoshi,Saga Tsuneo,Ishimori Takayoshi,Ishizu Koichi,Kawashima Hidekazu,Kawase Shigeto,Matsumoto Keiichi,Togashi Kaori

Publisher

Springer Science and Business Media LLC

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference26 articles.

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2. Wahl RL, Henry CA, Ethier SP. Serum glucose: effects on tumor and normal tissue accumulation of 2-[F-18]-fluoro-2-deoxy-d-glucose in rodents with mammary carcinoma. Radiology. 1992;183:643–7.

3. Torizuka T, Clavo AC, Wahl RL. Effect of hyperglycemia on in vitro tumor uptake of tritiated FDG, thymidine, l-methionine and l-leucine. J Nucl Med. 1997;38:382–6.

4. Zhao S, Kuge Y, Tsukamoto E, Mochizuki T, Kato T, Hikosaka K, et al. Effects of insulin and glucose loading on FDG uptake in experimental malignant tumours and inflammatory lesions. Eur J Nucl Med. 2001;28:730–5.

5. Lindholm P, Minn H, Leskinen-Kallio S, Bergman J, Ruotsalainen U, Joensuu H. Influence of the blood glucose concentration on FDG uptake in cancer—a PET study. J Nucl Med. 1993;34:1–6.

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