Development and Validation of LC–MS Method for the Estimation of N-Acetyl-Tryptophan and its Impurities Under Stress Conditions
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry,Analytical Chemistry
Link
http://link.springer.com/content/pdf/10.1007/s10337-019-03776-z.pdf
Reference14 articles.
1. Yu MW, Finlayson JS (1984) Quantitative determination of the stabilizers octanoic acid and N-acetyl-DL-tryptophan in human albumin products. J Pharm Sci 73:82–86. https://doi.org/10.1002/jps.2600730122
2. Zhu T, Chen Z, Zhan C-Y, Wang H-J, Mao L, Lian H-Z (2015) Determination of acetyl-tryptophan in human albumin by reversed-phase high performance liquid chromatography. Asian J Chem. https://doi.org/10.14233/ajchem.2015.17651
3. Fang L, Parti R, Hu P (2011) Characterization of N-acetyltryptophan degradation products in concentrated human serum albumin solutions and development of an automated high performance liquid chromatography-mass spectrometry method for their quantitation. J Chromatogr A 1218:7316–7324. https://doi.org/10.1016/j.chroma.2011.08.044
4. Hogan KL, Leiske D, Salisbury CM (2017) Characterization of N-acetyl-tryptophan degradation in protein therapeutic formulations. J Pharm Sci 106:3499–3506. https://doi.org/10.1016/j.xphs.2017.08.012
5. Nelis HJ, Lefevere MF, Baert E, D’Hoore W, De Leenheer AP (1985) Chromatographic determination of N-acetyl-DL-tryptophan and octanoic acid in human albumin solutions. J Chromatogr 333:381–387
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