Pharmacokinetic, Protein Binding, and Tissue Distribution Investigations of Viloxazine Enantiomers in Rat Plasma by HPLC–MS/MS Using Polysaccharide-Based Immobilized Chiral Column: A Preclinical Approach to Possible Chiral Switch
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry,Analytical Chemistry
Link
https://link.springer.com/content/pdf/10.1007/s10337-023-04293-w.pdf
Reference30 articles.
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2. Qian Z, Xu Y, Zheng L et al (2015) Enantiospecific determination of arotinolol in rat plasma by LC–MS/MS: Application to a stereoselective pharmacokinetic study. J Pharm Biomed Anal 102:299–304. https://doi.org/10.1016/j.jpba.2014.09.034
3. Chai T, Cui F, Di S et al (2021) New insights into cardiotoxicity induced by chiral fluoxetine at environmental-level: enantioselective arrhythmia in developmental zebrafish (Danio rerio). Environ Pollut 270:116182. https://doi.org/10.1016/j.envpol.2020.116182
4. Sun L, Xin L, Peng Z et al (2014) Toxicity and enantiospecific differences of two β-blockers, propranolol and metoprolol, in the embryos and larvae of zebrafish (Danio rerio). Environ Toxicol 29:1367–1378. https://doi.org/10.1002/tox.21867
5. Uchida R, Okamoto H, Ikuta N et al (2015) Enantioselective pharmacokinetics of α-lipoic acid in rats. IJMS 16:22781–22794. https://doi.org/10.3390/ijms160922781
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