Cytoreductive nephrectomy in metastatic renal cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Urology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11934-003-0055-6.pdf
Reference27 articles.
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2. Motzer R, Russo P: Systemic therapy for renal cell carcinoma. J Urol 2000, 163:408–417.
3. Figlin RA, Pierce WC, Kaboo R, et al.: Treatment of metastatic renal cell carcinoma with nephrectomy, interleukin-2 and cytokine-primed or CD8(+) selected tumor infiltrating lymphocytes from primary tumor. J Urol 1997, 158:740–745.
4. Greenlee RA, Murray T, Bolden S, Wingo PA: Cancer statistics 2000. CA Cancer J Clin 2000, 50:7–33.
5. Flanigan RC, Salmon SE, Blumenstein BA, et al.: Nephrectomy followed by interferon-alpha-2b compared with interferon alfa-2b alone for metastatic renal cell cancer. N Engl J Med 2001, 345:1655–1659. This paper represents the largest experience to date investigating the role of cytoreductive nephrectomy in metastatic renal cancer. A 50% increase in survival was demonstrated across all prestudy variables including PS, lung-only metastases, and evaluable disease.
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