Management of Intraductal Papillary Mucinous Neoplasms: Controversies in Guidelines and Future Perspectives
Author:
Funder
University Medical Center Rotterdam
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology
Link
http://link.springer.com/article/10.1007/s11938-018-0190-2/fulltext.html
Reference121 articles.
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2. Sessa F, Solcia E, Capella C, Bonato M, Scarpa A, Zamboni G, et al. Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. Virchows Arch. 1994;425:357–67.
3. Tulla KA, Maker AV. Can we better predict the biologic behavior of incidental IPMN? A comprehensive analysis of molecular diagnostics and biomarkers in intraductal papillary mucinous neoplasms of the pancreas. Langenbeck’s Arch Surg. 2017.
4. • Tanaka M, Chari S, Adsay V, Fernandez-del Castillo C, Falconi M, Shimizu M, et al. International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas. Pancreatology. 2006;6:17–32. The first multidisciplinary consensus guidelines on the clinical management of pancreatic cysts and defined high-risk features (mural nodule, main-duct dilation, size > 3 cm) related to increased risk of malignant progression.
5. • Tanaka M, Fernandez-del Castillo C, Adsay V, et al. International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas. Pancreatology. 2012;12:183–97. In response to their publication in 2006, extensive research led to new insights and the dichotomization of risk stratification (‘high-risk’ and ‘worrisome’ features). Recommending immediate resection in the case of high-risk features and a conservative approach in the case of worrisome features. Surveillance intervals are based on the the size of the cyst.
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