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Acute Exposure of Atmospheric Ultrafine Particles Induced Inflammation Response and Dysregulated TGFβ/Smads Signaling Pathway in ApoE−/− Mice

  • Published:2021-01-21 Issue:5 Volume:21 Page:410-421
  • ISSN:1530-7905
  • Container-title:Cardiovascular Toxicology
  • language:en
  • Short-container-title:Cardiovasc Toxicol

Author:

Li Kang,Yan Jun,Wang Shumei,Liang Xiaotian,Lin Bencheng,Tian Lei,Liu Huanliang,Liu Xiaohua,Xi Zhuge

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

The 13th Five-Year Plan for Military Medical Technology

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Toxicology,Molecular Biology

Reference35 articles.

1. Morawska, L., Ristovski, Z., Jayaratne, E., Keogh, D. U., & Ling, X. (2008). Ambient nano and ultrafine particles from motor vehicle emissions: Characteristics, ambient processing and implications on human exposure. Atmospheric Environment, 42(35), 8113–8138.

2. Chen, R., Hu, B., Liu, Y., Xu, J., Yang, G., Xu, D., et al. (2016). Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution. Biochimica Biophysica Acta, 1860(12), 2844–2855. https://doi.org/10.1016/j.bbagen.2016.03.019.

3. Calderon-Garciduenas, L., Engle, R., Mora-Tiscareno, A., Styner, M., Gomez-Garza, G., Zhu, H., et al. (2011). Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children. Brain and Cognition, 77(3), 345–355. https://doi.org/10.1016/j.bandc.2011.09.006.

4. Costello, S., Brown, D. M., Noth, E. M., Cantley, L., Slade, M. D., Tessier-Sherman, B., et al. (2014). Incident ischemic heart disease and recent occupational exposure to particulate matter in an aluminum cohort. Journal of Exposure Science & Environmental Epidemiology, 24(1), 82–88. https://doi.org/10.1038/jes.2013.47.

5. Farina, F., Lonati, E., Milani, C., Massimino, L., Ballarini, E., Donzelli, E., et al. (2019). In vivo comparative study on acute and sub-acute biological effects induced by ultrafine particles of different anthropogenic sources in BALB/c mice. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms20112805.

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