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Obesity Potentiates the Risk of Drug-Induced Long QT Syndrome - Preliminary Evidence from WNIN/Ob Spontaneously Obese Rat

  • Published:2021-07-24 Issue:10 Volume:21 Page:848-858
  • ISSN:1530-7905
  • Container-title:Cardiovascular Toxicology
  • language:en
  • Short-container-title:Cardiovasc Toxicol

Author:

Potnuri Ajay Godwin,Reddy Kallamadi Prathap,Suresh Pothani,Husain Gulam Mohammed,Kazmi Munawwar Husain,Harishankar Nemani

Funder

Indian Council of Medical Research

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Toxicology,Molecular Biology

Reference54 articles.

1. Wheelan, K., Mukharji, J., Rude, R. E., Poole, W. K., Gustafson, N., Thomas, L. J., Strauss, H. W., Jaffe, A. S., Muller, J. E., Roberts, R., Croft, C. H., Passamani, E. R., & Willerson, J. T. (1986). Sudden death and its relation to QT-interval prolongation after acute myocardial infarction: Two-year follow-up. American Journal of Cardiology, 57(10), 745–750. https://doi.org/10.1016/0002-9149(86)90606-5

2. Nachimuthu, S., Assar, M. D., & Schussler, J. M. (2012). Drug-induced QT interval prolongation: Mechanisms and clinical management. Therapeutic Advances in Drug Safety, 3(5), 241–253. https://doi.org/10.1177/2042098612454283

3. Li, M., & Ramos, L. G. (2017). Drug-induced QT prolongation and torsades de pointes. Pharmacy and Therapeutics, 42(7), 473–477.

4. Molokhia, M., Pathak, A., Lapeyre-Mestre, M., Caturla, L., Montastruc, J. L., McKeigue, P., & L’AssociationFrançaise des CentresRégionaux de Pharmacovigilance (CRPV). (2008). Case ascertainment and estimated incidence of drug-induced long-QT syndrome: Study in Southwest France. British Journal of Clinical Pharmacology, 66(3), 386–395. https://doi.org/10.1111/j.1365-2125.2008.03229.x

5. Sarganas, G., Garbe, E., Klimpel, A., Hering, R. C., Bronder, E., & Haverkamp, W. (2014). Epidemiology of symptomatic drug-induced long QT syndrome and Torsade de Pointes in Germany. Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology: Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, 16(1), 101–108. https://doi.org/10.1093/europace/eut214
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