Assessment of Safety Margin of an Antipsychotic Drug Haloperidol for Torsade de Pointes Using the Chronic Atrioventricular Block Dogs-Reference-Cited by-同舟云学术

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Assessment of Safety Margin of an Antipsychotic Drug Haloperidol for Torsade de Pointes Using the Chronic Atrioventricular Block Dogs

Published:2016-10-13 Issue:3 Volume:17 Page:319-325
ISSN:1530-7905
Container-title:Cardiovascular Toxicology
language:en
Short-container-title:Cardiovasc Toxicol

Author:

Izumi-Nakaseko Hiroko,Nakamura Yuji,Cao Xin,Wada Takeshi,Ando Kentaro,Sugiyama Atsushi

Funder

JSPS KAKENHI

the Research Promotion Grant from Toho University Graduate School of Medicine

Toho University Joint Research Fund

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Toxicology,Molecular Biology

Link

http://link.springer.com/article/10.1007/s12012-016-9388-5/fulltext.html

Reference28 articles.

1. Khot, V., DeVane, C. L., Korpi, E. R., Venable, D., Bigelow, L. B., Wyatt, R. J., et al. (1993). The assessment and clinical implications of haloperidol acute-dose, steady-state, and withdrawal pharmacokinetics. Journal of Clinical Psychopharmacology, 13, 120–127.

2. Meyer-Massetti, C., Cheng, C. M., Sharpe, B. A., Meier, C. R., & Guglielmo, B. J. (2010). The FDA extended warning for intravenous haloperidol and torsades de pointes: How should institutions respond? Journal of Hospital Medicine, 5, E8–E16.

3. Polak, S., Wiśniowska, B., & Brandys, J. (2009). Collation, assessment and analysis of literature in vitro data on hERG receptor blocking potency for subsequent modeling of drugs’ cardiotoxic properties. Journal of Applied Toxicology, 29, 183–206.

4. Sugiyama, A., Satoh, Y., & Hashimoto, K. (2001). In vivo canine model comparison of cardiohemodynamic and electrophysiological effects of a new antipsychotic drug aripiprazole (OPC-14597) to haloperidol. Toxicology and Applied Pharmacology, 173, 120–128.

5. Mörtl, D., Agneter, E., Krivanek, P., Koppatz, K., & Todt, H. (2003). Dual rate-dependent cardiac electrophysiologic effects of haloperidol: Slowing of intraventricular conduction and lengthening of repolarization. Journal of Cardiovascular Pharmacology, 41, 870–879.

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