Nuclear Receptors in Vascular Biology
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11883-015-0507-8.pdf
Reference57 articles.
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3. Bishop-Bailey D, Hla T. Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. J Biol Chem. 1999;274(24):17042–8.
4. Piqueras L, Reynolds AR, Hodivala-Dilke KM, et al. Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis. Arterioscler Thromb Vasc Biol. 2007;27(1):63–9.
5. Swales KE, Moore R, Truss NJ, et al. Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress. Cardiovasc Res. 2012;93(4):674–81. This paper shows the expression of PXR in human and rodent vascular cells and tissue. Acute vascular activation of PXR led to a co-ordinate programme of drug metabolism, transport, and oxidant defence.
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