The Role of Red Yeast Rice for the Physician
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11883-010-0145-0.pdf
Reference60 articles.
1. Ma J, Li Y, Li J, et al. Constituents of Red Yeast Rice, a Traditional Chinese Food and Medicine. J. Agric Food Chem. 2000;48:5220–5225.
2. Van Tieghem P. Monascus, genre nouveau de l’ordre des Ascomycetes. Bull Soc France. 1884;31:226–231.
3. Went FA. Monascus purpureus le chmpignon de l’angquac une nouvelle thelobolee. Ann Soc Nat Bot. 1895;8:1–17.
4. •• Becker DJ, Gordon RY, Halbert SC, French B, Morris PB, Rader DJ. Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial. Ann Intern Med. 2009;150(12):830–9, W147-9. This is the first trial evaluating red yeast rice as a lipid-lowering therapy for patients with a history of SAMs. It randomized 62 patients with a history of intolerance to one or more statins to a lifestyle-modification program and either red yeast rice or placebo and followed them for 24 weeks. The red yeast rice group had a significant decrease in LDL-C compared with placebo at 12 and 24 weeks, with no increase incidence in myalgias.
5. •• Becker DJ, Gordon RY, Morris PB, et al. Simvastatin vs therapeutic lifestyle changes and supplements: randomized primary prevention trial. Mayo Clin Proc. 2008;83(7):758–64. This trial that randomized 74 patients to either usual therapy (simvastatin) or an alternative regimen (red yeast rice, fish oil, and a lifestyle-modification program) and followed them for 12 weeks. There were no differences between the groups in LDL-C levels and the alternative-regimen group had significant decreases in weight and triglycerides.
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