Competition between two enzymes for substrate removal in liver: Modulating effects due to substrate recruitment of hepatocyte activity

Author:

Morris Marilyn E.,Pang K. Sandy

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Reference43 articles.

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3. S. R. Howell, G. A. Hazelton, and C. D. Klaassen. Depletion of hepatic UDP-glucuronic acid by drugs that are glucuronidated.J. Pharmacol. Exp. Ther. 236:610–614 (1986).

4. C. A. Goresky, W. H. Ziegler, and G. G. Bach. Capillary exchange modeling: Barrier-limited and flow-limited distribution.Circ. Res. 27:739–747 (1970).

5. I. A. M. DeLannoy and K. S. Pang. A commentary. The presence of diffusional barriers on metabolite kinetics. 1. Enalaprilat as a generatedversus preformed metabolite.Drug Metab. Dispos. 14:513–520 (1986).

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