Determination of muscarinic agonist potencies at M1 and M2 muscarinic receptors in a modified pithed rat preparation

Author:

Angeli P.,Brasili L.,Cantalamessa F.,Marucci G.,Wess J.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Reference19 articles.

1. Angeli P, Brasili L, Giannella MT, Gualtieri F, Picchio MT, Teodori E (1988) Chiral muscarinic agonists possessing a 1,3-oxathiolane nucleus: enantio- and tissue-selectivity on isolated preparations of guinea-pig ileum and atria and of rat urinary bladder. Naunyn-Schmiedeberg's Arch Pharmacol 337:241–245

2. Bonner TI (1989) Identification of a family of muscarinic acetylcholine receptor genes. Trends Neurosci 12:148–151

3. de Jonge A, Doods HN, Riezebos J, van Zwieten PA (1986) Heterogeneity of muscarinic binding sites in rat brain, submandibular gland and atrium. Br J Pharmacol 89:551P

4. Doods HN, Mathy MJ, Davidesko D, van Charldorp KJ, de Jonge A, Van Zwieten PA (1987) Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors. J Pharmacol Exp Ther 242:257–262

5. Giachetti A, Micheletti R, Montagna E (1986) Cardioselective profile of AF-DX 116, a muscarine M2 receptor antagonist. Life Sci 38:1663–1672

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