L-alanine transport in isolated cells of interscapular brown adipose tissue in rat-Reference-Cited by-同舟云学术

L-alanine transport in isolated cells of interscapular brown adipose tissue in rat

Published:1991-04-01 Issue:2 Volume:11 Page:65-71
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Rodríguez-Martín A.¹,Remesar X.¹

Affiliation:

1. Unitat de Bioquímica i Biologia Molecular B. Departament de Boquímica i Fisiologia, Universitat de Barcelona, 08071 Barcelona, Spain

Abstract

The pattern of L-alanine uptake in isolated cells of interscapular brown adipose tissue has been determined. The uptake can be divided into the diffusion component (Kd=0.55 min−1) and a saturable Na+-dependent transport (KM=0.87 mM and Vmax=155 nmol/min/106 cells). The saturable component can be subdivided into MeAIB-sensitive (KM=1.63 mM and Vmax=162 nmol/min/106 cells) and MeAIB-insensitive (KM=3.2 mM and Vmax=39.5 nmol/min/106 cells). This kinetic pattern could indicate the presence of transport system (s) that resemble the commonly described transport systems for alanine uptake in several tissues.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/11/2/65/468368/bsr0110065.pdf

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