Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21

Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling

Published:2021-08-28 Issue:5 Volume:52 Page:905-918
ISSN:1567-2379
Container-title:Journal of Molecular Histology
language:en
Short-container-title:J Mol Histol

Author:

Song Juan-Juan,Yang Mei,Liu Ying,Song Jia-Wei,Liu Xiao-Yan,Miao Ran,Zhang Zhen-Zhou,Liu Yu,Fan Yi-Fan,Zhang Qian,Dong Ying,Yang Xin-Chun,Zhong Jiu-Chang^ORCID

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,General Medicine,Physiology,Histology

Link

https://link.springer.com/content/pdf/10.1007/s10735-021-10011-3.pdf

Reference37 articles.

1. Agarwal R (2003) Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade. Am J Physiol Renal Physiol 284(4):F863–F869. https://doi.org/10.1152/ajprenal.00385.2002

2. Bersi MR, Bellini C, Wu J, Montaniel KRC, Harrison DG, Humphrey JD (2016) Excessive adventitial remodeling leads to early aortic maladaptation in angiotensin-induced hypertension. Hypertension 67:890–896. DOI:https://doi.org/10.1161/HYPERTENSIONAHA.115.06262

3. Chai X, Sun D, Han Q, Yi L, Wu Y, Liu X (2018) Hypoxia induces pulmonary arterial fibroblast proliferation, migration, differentiation and vascular remodeling via the PI3K/Akt/p70S6K signaling pathways. Int J Mol Med 41:2461–2472. DOI:https://doi.org/10.3892/ijmm.2018.3462

4. Domouzoglou EM, Naka KK, Vlahos AP, Papafaklis MI, Michalis LK, Tsatsoulis A, Marators-Flier E (2015) Fibroblast growth factors in cardiovascular disease: the emerging role of FGF21. Am J Physiol Heart Circ Physiol 309:H1029–H1038. DOI:https://doi.org/10.1152/ajpheart.00527.2015

5. Fisher FM, Maratos-Flier E (2016) Understanding the physiology of FGF21. Annu Rev Physiol 78:223–241. https://doi.org/10.1146/annurev-physiol-021115-105339

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