Alzheimer’s disease: the controversial approval of Aducanumab-Reference-Cited by-同舟云学术

Alzheimer’s disease: the controversial approval of Aducanumab

Published:2021-07-29 Issue:8 Volume:42 Page:3069-3070
ISSN:1590-1874
Container-title:Neurological Sciences
language:en
Short-container-title:Neurol Sci

Author:

Tagliavini Fabrizio,Tiraboschi Pietro,Federico Antonio

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health,Neurology (clinical),Dermatology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s10072-021-05497-4.pdf

Reference9 articles.

1. Hardy JA, Higgins GA (1992) Alzheimer’s disease: the amyloid cascade hypothesis. Science 256(5054):184–185. https://doi.org/10.1126/science.1566067

2. Panza F, Lozupone M, Logroscino G, Imbimbo BP (2019) A critical appraisal of amyloid-beta-targeting therapies for Alzheimer disease. Nat Rev Neurol 15:73–88. https://doi.org/10.1038/s41582-018-0116-6

3. FDA. FDA’s decision to approve new treatment for Alzheimer’s disease. 2021 Jul 6 [cited 2021 Jun 14]. Available from: https://www.fda.gov/drugs/news-events-human-drugs/fdas-decision-approve-new-treatment-alzheimers-disease. Accessed 21 Jul 2021

4. Sevigny J, Chiao P, Bussière T, Weinreb PH, Williams L et al (2016) The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease. Nature 537(7618):50–56. https://doi.org/10.1038/nature19323

5. Biogen (2019) EMERGE and EMERGE and ENGAGE topline results: two phase 3 studies to evaluate aducanumab in patients with early Alzheimer’s disease. Available from: https://investors.biogen.com/static-files/ddd45672-9c7e-4c99-8a06-3b557697c06f. Accessed 21 Jul 2021

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