Role of 5α-reductase inhibitors in modulation of the analgesic effects of morphine: an emerging concept in pain management
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Neurology (clinical),Dermatology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s10072-012-1016-y.pdf
Reference5 articles.
1. Sharif A, Shoae-Hassani A, Sharif S, Banafshe HR, Mortazavi-Tabatabaei SA, Verdi J (2012) 5 α-reductase 1 regulates spinal cord testosterone after morphine administration. Neurol Sci. doi: 10.1007/s10072-012-0936-x
2. Moradi-Azani M, Ahmadiani A, Amini H (2011) Increase in formalin-induced tonic pain by 5 alpha-reductase and aromatase inhibition in female rats. Pharmacol Biochem Behav 98:62–66
3. Amini H, Ahmadiani A (2005) In vivo evidence for an increase in 5 alpha-reductase activity in the rat central nervous system following morphine exposure. Int J Dev Neurosci 23:621–626
4. Duborija-Kovacevic N, Jakovljevic V, Sabo A, Tomic Z (2008) Anti-nociceptive and anti-inflammatory properties of 5 alpha-reductase inhibitor finasteride in experimental animals. Eur J Drug Metab Pharmacokinet 33:181–186
5. Verdi J, Ahmadiani A (2007) Finasteride, a 5 alpha-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat. Horm Behav 51:605–610
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