Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation

Author:

Glasscock Edward,Voigt Niels,McCauley Mark D.,Sun Qiang,Li Na,Chiang David Y.,Zhou Xiao-Bo,Molina Cristina E.,Thomas Dierk,Schmidt Constanze,Skapura Darlene G.,Noebels Jeffrey L.,Dobrev Dobromir,Wehrens Xander H. T.

Funder

National Institutes of Health

Muscular Dystrophy Association

American Heart Association

Deutsche Forschungsgemeinschaft

German Federal Ministry of Education and Research

the European Network for Translational Research in Atrial Fibrillation

Fondation Leducq

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference52 articles.

1. Balse E, El-Haou S, Dillanian G, Dauphin A, Eldstrom J, Fedida D, Coulombe A, Hatem SN (2009) Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes. Proc Natl Acad Sci 106:14681–14686. doi: 10.1073/pnas.0902809106

2. Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey G (1996) K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 384:78–80. doi: 10.1038/384078a0

3. Boycott HE, Barbier CSM, Eichel CA, Costa KD, Martins RP, Louault F, Dilanian G, Coulombe A, Hatem SN, Balse E (2013) Shear stress triggers insertion of voltage-gated potassium channels from intracellular compartments in atrial myocytes. Proc Natl Acad Sci 110:E3955–E3964. doi: 10.1073/pnas.1309896110

4. Brundel BJ, Van Gelder IC, Henning RH, Tieleman RG, Tuinenburg AE, Wietses M, Grandjean JG, Van Gilst WH, Crijns HJ (2001) Ion channel remodeling is related to intraoperative atrial effective refractory periods in patients with paroxysmal and persistent atrial fibrillation. Circulation 103:684–690. doi: 10.1161/01.CIR.103.5.684

5. Brundel BJ, Van Gelder IC, Henning RH, Tuinenburg AE, Wietses M, Grandjean JG, Wilde AA, Van Gilst WH, Crijns HJ (2001) Alterations in potassium channel gene expression in atria of patients with persistent and paroxysmal atrial fibrillation: differential regulation of protein and mRNA levels for K+ channels. J Am Coll Cardiol 37:926–932. doi: 10.1016/S0735-1097(00)01195-5

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