Exercise does not activate the β3 adrenergic receptor–eNOS pathway, but reduces inducible NOS expression to protect the heart of obese diabetic mice

Author:

Kleindienst Adrien,Battault Sylvain,Belaidi Elise,Tanguy Stephane,Rosselin Marie,Boulghobra Doria,Meyer Gregory,Gayrard Sandrine,Walther Guillaume,Geny Bernard,Durand Gregory,Cazorla Olivier,Reboul Cyril

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference49 articles.

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2. Aragón JP, Condit ME, Bhushan S, Predmore BL, Patel SS, Grinsfelder DB, Gundewar S, Jha S, Calvert JW, Barouch LA, Lavu M, Wright HM, Lefer DJ (2011) β3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation. J Am Coll Cardiol 58:2683–2691. doi: 10.1016/j.jacc.2011.09.033

3. Barba I, Chavarria L, Ruiz-Meana M, Mirabet M, Agulló E, Garcia-Dorado D (2009) Effect of intracellular lipid droplets on cytosolic Ca2+ and cell death during ischaemia-reperfusion injury in cardiomyocytes. J Physiol 587:1331–1341. doi: 10.1113/jphysiol.2008.163311

4. Belaidi E, Thomas A, Bourdier G, Moulin S, Lemarié E, Levy P, Pépin JL, Korichneva I, Godin-Ribuot D, Arnaud C (2016) Endoplasmic reticulum stress as a novel inducer of hypoxia inducible factor-1 activity: its role in the susceptibility to myocardial ischemia-reperfusion induced by chronic intermittent hypoxia. Int J Cardiol 210:45–53. doi: 10.1016/j.ijcard.2016.02.096

5. Birenbaum A, Tesse A, Loyer X, Michelet P, Andriantsitohaina R, Heymes C, Riou B, Amour J (2008) Involvement of β3-adrenoceptor in altered beta-adrenergic response in senescent heart: role of nitric oxide synthase 1-derived nitric oxide. Anesthesiology 109:1045–1053. doi: 10.1097/ALN.0b013e31818d7e5a

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