Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening-Reference-Cited by-同舟云学术

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Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening

Published:2007-12-13 Issue:3 Volume:103 Page:274-284
ISSN:0300-8428
Container-title:Basic Research in Cardiology
language:en
Short-container-title:Basic Res Cardiol

Author:

Bhamra Gurpreet S.,Hausenloy Derek J.,Davidson Sean M.,Carr Richard D.,Paiva Marta,Wynne Abigail M.,Mocanu Mihaela M.,Yellon Derek M.

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

http://link.springer.com/content/pdf/10.1007/s00395-007-0691-y.pdf

Reference57 articles.

1. (1998) Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet 352:854–865

2. Abdallah Y, Gkatzoflia A, Gligorievski D, Kasseckert S, Euler G, Schluter KD, Schafer M, Piper HM, Schafer C (2006) Insulin protects cardiomyocytes against reoxygenation-induced hypercontracture by a survival pathway targeting SR Ca2+ storage. Cardiovasc Res 70:346–353

3. Alserius T, Hammar N, Nordqvist T, Ivert T (2006) Risk of death or acute myocardial infarction 10 years after coronary artery bypass surgery in relation to type of diabetes. Am Heart J 152:599–605

4. An D, Kewalramani G, Chan JK, Qi D, Ghosh S, Pulinilkunnil T, Abrahani A, Innis SM, Rodrigues B (2006) Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3. Diabetologia 49:2174–2184

5. Argaud L, Gateau-Roesch O, Raisky O, Loufouat J, Robert D, Ovize M (2005) Postconditioning inhibits mitochondrial permeability transition. Circulation 111:194–197

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