Effect of COMBinAtion therapy with remote ischemic conditioning and exenatide on the Myocardial Infarct size: a two-by-two factorial randomized trial (COMBAT-MI)

Author:

García del Blanco Bruno,Otaegui Imanol,Rodríguez-Palomares José F.,Bayés-Genis Antoni,Fernández-Nofrerías Eduard,Vilalta del Olmo Victoria,Carrillo Xavier,Ibáñez Borja,Worner Fernando,Casanova Juan,Pueo Eva,González-Juanatey Jose R.,López-Pais Javier,Bardají Alfredo,Bonet Gil,Fuertes Mónica,Rodríguez-Sinovas AntonioORCID,Ruiz-Meana Marisol,Inserte Javier,Barba Ignasi,Gómez-Talavera Sandra,Martí Gerard,Serra Bernat,Bellera Neus,Ojeda-Ramos Manuel,Cuellar Hug,Valente Filipa,Carmona Maria Ángeles,Miró-Casas Elisabet,Marsal Josep R.,Sambola Antonia,Lidón Rosa M.,Bañeras Jordi,Elízaga Jaime,Padilla Ferran,Barrabés José A.,Hausenloy Derek J.,Ferreira-González Ignacio,García-Dorado David

Funder

Instituto de Salud Carlos III

Departament de Salut, Generalitat de Catalunya

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Reference50 articles.

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2. Barrabes JA, Inserte J, Mirabet M, Quiroga A, Hernando V, Figueras J, Garcia-Dorado D (2010) Antagonism of P2Y12 or GPIIb/IIIa receptors reduces platelet-mediated myocardial injury after ischaemia and reperfusion in isolated rat hearts. Thromb Haemost 104:128–135. https://doi.org/10.1160/TH09-07-0440

3. Bose AK, Mocanu MM, Carr RD, Brand CL, Yellon DM (2005) Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury. Diabetes 54:146–151. https://doi.org/10.2337/diabetes.54.1.146

4. Botker HE, Hausenloy D, Andreadou I, Antonucci S, Boengler K, Davidson SM, Deshwal S, Devaux Y, Di Lisa F, Di Sante M, Efentakis P, Femminò S, García-Dorado D, Giricz Z, Ibanez B, Iliodromitis E, Kaludercic N, Kleinbongard P, Neuhaüser M, Ovize M, Pagliaro P, Rahbek-Schmidt M, Ruiz-Meana M, Schlüter KD, Schulz R, Skyschally A, Wilder C, Yellon DM, Ferdinandy P, Heusch G (2018) Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection. Basic Res Cardiol 113:39. https://doi.org/10.1007/s00395-018-0696-8

5. Botker HE, Kharbanda R, Schmidt MR, Bottcher M, Kaltoft AK, Terkelsen CJ, Munk K, Andersen NH, Hansen TM, Trautner S, Lassen JF, Christiansen EH, Krusell LR, Kristensen SD, Thuesen L, Nielsen SS, Rehling M, Sorensen HT, Redington AN, Nielsen TT (2010) Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomised trial. Lancet 375:727–734. https://doi.org/10.1016/S0140-6736(09)62001-8

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