Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression-Reference-Cited by-同舟云学术

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Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression

Published:2016-02-18 Issue:2 Volume:111 Page:
ISSN:0300-8428
Container-title:Basic Research in Cardiology
language:en
Short-container-title:Basic Res Cardiol

Author:

Lindau Alexandra,Härdtner Carmen,Hergeth Sonja P.,Blanz Kelly Daryll,Dufner Bianca,Hoppe Natalie,Anto-Michel Nathaly,Kornemann Jan,Zou Jiadai,Gerhardt Louisa M. S.,Heidt Timo,Willecke Florian,Geis Serjosha,Stachon Peter,Wolf Dennis,Libby Peter,Swirski Filip K.,Robbins Clinton S.,McPheat William,Hawley Shaun,Braddock Martin,Gilsbach Ralf,Hein Lutz,von zur Mühlen Constantin,Bode Christoph,Zirlik Andreas,Hilgendorf Ingo

Funder

Deutsche Forschungsgemeinschaft (DE)

AstraZeneca (GB)

Publisher

Springer Science and Business Media LLC

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

http://link.springer.com/content/pdf/10.1007/s00395-016-0535-8.pdf

Reference20 articles.

1. Cochain C, Zernecke A (2015) Macrophages and immune cells in atherosclerosis: recent advances and novel concepts. Basic Res Cardiol 110:34. doi: 10.1007/s00395-015-0491-8

2. Choi SH, Harkewicz R, Lee JH, Boullier A, Almazan F, Li AC, Witztum JL, Bae YS, Miller YI (2009) Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake. Circ Res 104:1355–1363. doi: 10.1161/CIRCRESAHA.108.192880

3. Cook AD, Turner AL, Braine EL, Pobjoy J, Lenzo JC, Hamilton JA (2011) Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritis. Arthritis Rheum 63:2340–2351. doi: 10.1002/art.30354

4. Del Rincon I, Polak JF, O’Leary DH, Battafarano DF, Erikson JM, Restrepo JF, Molina E, Escalante A (2015) Systemic inflammation and cardiovascular risk factors predict rapid progression of atherosclerosis in rheumatoid arthritis. Ann Rheum Dis 74:1118–1123. doi: 10.1136/annrheumdis-2013-205058

5. Genovese MC, van der Heijde DM, Keystone EC, Spindler AJ, Benhamou C, Kavanaugh A, Fudman E, Lampl K, O’Brien C, Duffield EL, Poiley J, Weinblatt ME (2014) A phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of 2 dosing regimens of fostamatinib in patients with rheumatoid arthritis with an inadequate response to a tumor necrosis factor-alpha antagonist. J Rheumatol 41:2120–2128. doi: 10.3899/jrheum.140238

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