Recent Findings from Mendelian Randomization Studies of Cardiovascular Disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/s12170-010-0127-3.pdf
Reference48 articles.
1. Davey Smith G, Ebrahim S: ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 2003, 32:1–22.
2. •• Sheehan NA, Didelez V, Burton PR, Tobin MD: Mendelian randomisation and causal inference in observational epidemiology. PLoS Medicine 2008, 5:e177. This article describes the Mendelian randomization concept, summarizes key assumptions and limitations, and provides several examples to illustrate how Mendelian randomization is used in practice.
3. Pearson TA, Manolio TA: How to interpret a genome-wide association study. JAMA 2008, 299:1335–1344.
4. Greenland S: An introduction to instrumental variables for epidemiologists. Int J Epidemiol 2000, 29:722–729.
5. Katan MB: Apolipoprotein E isoforms, serum cholesterol, and cancer. Lancet 1986, i:507–508.
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1. Mendelian Randomization: Application to Cardiovascular Disease;Current Hypertension Reports;2011-12-13
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