Diabetes in the Elderly
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/s12170-010-0117-5.pdf
Reference22 articles.
1. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 1993, 329:977–986.
2. Botts AM, Munshi M: Diabetes in the Elderly. Current Cardiovascular Risk Reports 2008, 2:382–389.
3. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998, 352:837–853.
4. Nathan DM, Cleary PA, Backlund JY, et al.: Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005, 353:2643–2653.
5. •• Holman RR, Paul SK, Bethel MA, et al.: 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008, 359:1577–1589. This study was comprised of the post-trial monitoring of 3277 patients of 4209 original randomized patients in the United Kingdom Prospective Diabetes study. The results of the study showed loss of benefits in A1C that was seen during the original trial period in the intensively treated group. However, there was a continued reduction in microvascular risk and emergent reduction in risk from MI and death from any cause during the 10 years of post-trial follow-up in the intensively treated group.
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