Supplement to “Effect and Safety of Hydroxysafflor Yellow A for Injection in Patients with Acute Ischemic Stroke of Blood Stasis Syndrome: A Phase II, Multicenter, Randomized, Double-Blind, Multiple-Dose, Active-Controlled Clinical Trial”
Author:
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s11655-024-3911-5.pdf
Reference8 articles.
1. Hu MZ, Zhou ZY, Zhou ZY, Lu H, Gao M, Liu LM, et al. Effect and safety of Hydroxysafflor Yellow A for Injection in patients with acute ischemic stroke of blood stasis syndrome: a phase II, multicenter, randomized, double-blind, multiple-dose, active-controlled clinical trial. Chin J Integr Med 2020;26:420–427.
2. Lv Y, Fu L. The potential mechanism for Hydroxysafflor yellow A attenuating blood-brain barrier dysfunction via tight junction signaling pathways excavated by an integrated serial affinity chromatography and shotgun proteomics analysis approach. Neurochem Int 2018;112:38–48.
3. Ye SY, Gao WY. Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in rats. Arch Pharm Res 2008;31:1010–1015.
4. Lv Y, Qian Y, Ouyang A, Fu L. Hydroxysafflor yellow A attenuates neuron damage by suppressing the lipopolysaccharide-induced TLR4 pathway in activated microglial cells. Cell Mol Neurobiol 2016;36:1241–1256.
5. Zhao F, Wang P, Jiao Y, Zhang X, Chen D, Xu H. Hydroxysafflor yellow A: a systematical review on botanical resources, physicochemical properties, drug delivery system, pharmacokinetics, and pharmacological effects. Front Pharmacol 2020;11:579332.
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