Saeng-Kankunbi-Tang (生肝健脾汤) protects liver against oxidative damage through activation of ERK/Nrf2 pathway

Author:

Lee In Woo,Choi Hee Yoon,Lee Ju-Hee,Park Sun-Dong,Kim Seung Mo,Ku Sae Kwang,Zhao Rong-jie,Kim Sang Chan,Kim Young Woo,Choi Hong Sik

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Complementary and alternative medicine,General Medicine

Reference35 articles.

1. Kurzawski M, Dziedziejko V, Urasiska E, Post M, Wójcicki M, Mitkiewski J, et al. Nuclear factor erythroid 2-like 2 (Nrf2) expression in end-stage liver disease. Environ Toxicol Pharmacol 2012;34:87–95.

2. Rushmore TH, Morton MR, Pickett CB. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 1991;266:11632–11639.

3. Moi P, Chan K, Asunis I, Cao A, Kan YW. Isolation of NFE2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/ AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 1994;91:9926–9930.

4. Tong KI, Kobayashi A, Katsuoka F, Yamamoto M. Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism. Biol Chem 2006;387:1311–1320.

5. Hwang SJ, Choi HS, Kim SM, Woo CH. Effects of Saeng kankeonbi tang on prevention of hyperlipidemia and liver damage induced by alcohol. Kor J Herbol 2009;24:9–15.

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