Ibuprofen Exerts Antiepileptic and Neuroprotective Effects in the Rat Model of Pentylenetetrazol-Induced Epilepsy via the COX-2/NLRP3/IL-18 Pathway-Reference-Cited by-同舟云学术

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Ibuprofen Exerts Antiepileptic and Neuroprotective Effects in the Rat Model of Pentylenetetrazol-Induced Epilepsy via the COX-2/NLRP3/IL-18 Pathway

Published:2020-08-13 Issue:10 Volume:45 Page:2516-2526
ISSN:0364-3190
Container-title:Neurochemical Research
language:en
Short-container-title:Neurochem Res

Author:

Liu Rui,Wu Shuhua,Guo Chong,Hu Zhongbo,Peng Jiangtao,Guo Ke,Zhang Xinfan,Li Jianmin

Funder

National Natural Science Foundation of China

Shandong Medical and Health Technology Development Plan

Binzhou Medical University Science and Technology Plan Project

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,General Medicine,Biochemistry

Link

https://link.springer.com/content/pdf/10.1007/s11064-020-03109-9.pdf

Reference45 articles.

1. Rana A, Musto AE (2018) The role of inflammation in the development of epilepsy. J Neuroinflamm 15(1):144

2. Mazarati AM, Lewis ML, Pittman QJ (2017) Neurobehavioral comorbidities of epilepsy: role of inflammation. Epilepsia 58(Suppl 3):48–56

3. Malik A, Kanneganti TD (2017) Inflammasome activation and assembly at a glance. J Cell Sci 130(23):3955–3963

4. Rathinam VAK, Fitzgerald KA (2016) Inflammasome complexes: emerging mechanisms and effector functions. Cell 165(4):792–800

5. Shao BZ, Xu ZQ, Han BZ et al (2015) NLRP3 inflammasome and its inhibitors: a review. Front Pharmacol 6:262

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