Competition, Selectivity and Efficacy of Analogs of A-84543 for Nicotinic Acetylcholine Receptors with Repositioning of Pyridine Nitrogen-Reference-Cited by-同舟云学术

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Competition, Selectivity and Efficacy of Analogs of A-84543 for Nicotinic Acetylcholine Receptors with Repositioning of Pyridine Nitrogen

Published:2015-10 Issue:10 Volume:40 Page:2131-2142
ISSN:0364-3190
Container-title:Neurochemical Research
language:en
Short-container-title:Neurochem Res

Author:

Ogunjirin Adebowale E.,Fortunak Joseph M.,Brown LaVerne L.,Xiao Yingxian,Dávila-García Martha I.

Funder

National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,General Medicine,Biochemistry

Link

http://link.springer.com/content/pdf/10.1007/s11064-015-1705-z.pdf

Reference54 articles.

1. Jensen AA, Bente F, Liljefors T, Krogsgard-Larsen P (2005) Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. J Med Chem 48(15):4705–4745

2. Hurst R, Rollema H, Bertrand D (2013) Nicotinic acetylcholine receptors: from basic science to therapeutics. Pharmacol Ther 137(1):22–54

3. Dineley KT, Pandya AA, Yakel JL (2015) Nicotinic ACh receptors as therapeutic targets in CNS disorders. Trends Pharmacol Sci 36(2):96–108

4. Becchetti A, Aracri P, Meneghini S, Brusco S, Amadeo A (2015) The role of nicotinic acetylcholine receptors in autosomal dominant nocturnal frontal lobe epilepsy. Front Physiol 6:22. doi: 10.3389/fphys.2015.00022

5. Martelli D, McKinley MJ, McAllen RM (2014) The cholinergic anti-inflammatory pathway: a critical review. Auton Neurosci 182:65–69

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1. A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in Its Interactions with α7 and α4β2 Nicotinic Acetylcholine Receptors;Molecular Pharmacology;2020-05-30

2. Site-Selective Switching Strategies to Functionalize Polyazines;Journal of the American Chemical Society;2018-05-24

3. From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor;European Journal of Medicinal Chemistry;2017-01

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