Menaquinone-4 Alleviates Neurological Deficits Associated with Intracerebral Hemorrhage by Preserving Corticospinal Tract in Mice

Author:

Ushida Keisuke,Kinoshita Keita,Ichihara Yusei,Hirata Yuma,Kurauchi YukiORCID,Seki TakahiroORCID,Katsuki HiroshiORCID

Funder

Japan Society for the Promotion of Science

Smoking Research Foundation

Publisher

Springer Science and Business Media LLC

Reference35 articles.

1. GBD 2019 Stroke Collaborators (2021) Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the global burden of Disease Study 2019. Lancet Neurol 20:795–820. https://doi.org/10.1016/S1474-4422(21)00252-0

2. Cordonnier C, Demchuk A, Ziai W, Anderson CS (2018) Intracerebral haemorrhage: current approaches to acute management. Lancet 392:1257–1268. https://doi.org/10.1016/S0140-6736(18)31878-6

3. Greenberg SM, Ziai WC, Cordonnier C, Dowlatshahi D, Francis B, Goldstein JN, Hemphill JC 3rd, Johnson R, Keigher KM, Mack WJ, Mocco J, Newton EJ, Ruff IM, Sansing LH, Schulman S, Selim MH, Sheth KN, Sprigg N, Sunnerhagen KS, American Heart Association/American Stroke Association (2022) 2022 Guideline for the management of patients with spontaneous intracerebral hemorrhage: a Guideline from the American Heart Association/American Stroke Association. Stroke 53:e282–e361. https://doi.org/10.1161/STR.0000000000000407

4. Matsushita H, Hijioka M, Hisatsune A, Isohama Y, Shudo K, Katsuki H (2012) Natural and synthetic retinoids afford therapeutic effects on intracerebral hemorrhage in mice. Eur J Pharmacol 683:125–131. https://doi.org/10.1016/j.ejphar.2012.03.023

5. Matsushita H, Hijioka M, Ishibashi H, Anan J, Kurauchi Y, Hisatsune A, Seki T, Shudo K, Katsuki H (2014) Suppression of CXCL2 upregulation underlies the therapeutic effect of the retinoid Am80 on intracerebral hemorrhage in mice. J Neurosci Res 92:1024–1034. https://doi.org/10.1002/jnr.23379

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