Pre-stroke Metformin Treatment is Neuroprotective Involving AMPK Reduction-Reference-Cited by-同舟云学术

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Pre-stroke Metformin Treatment is Neuroprotective Involving AMPK Reduction

Published:2016-06-27 Issue:10 Volume:41 Page:2719-2727
ISSN:0364-3190
Container-title:Neurochemical Research
language:en
Short-container-title:Neurochem Res

Author:

Deng Tian,Zheng Yan-Rong,Hou Wei-Wei,Yuan Yang,Shen Zhe,Wu Xiao-Li,Chen Ying,Zhang Li-San,Hu Wei-Wei,Chen Zhong,Zhang Xiang-Nan

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Research Project of Department of Education of Zhejiang Province

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,General Medicine,Biochemistry

Link

http://link.springer.com/content/pdf/10.1007/s11064-016-1988-8.pdf

Reference32 articles.

1. Cheng YY, Leu HB, Chen TJ, Chen CL, Kuo CH, Lee SD, Kao CL (2014) Metformin-inclusive therapy reduces the risk of stroke in patients with diabetes: a 4-year follow-up study. J Stroke Cerebrovasc Dis 23:e99–e105

2. Liu Y, Tang G, Li Y, Wang Y, Chen X, Gu X, Zhang Z, Wang Y, Yang GY (2014) Metformin attenuates blood–brain barrier disruption in mice following middle cerebral artery occlusion. J Neuroinflammation 11:177

3. Ashabi G, Khalaj L, Khodagholi F, Goudarzvand M, Sarkaki A (2015) Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia. Metab Brain Dis 30:747–754

4. Jin Q, Cheng J, Liu Y, Wu J, Wang X, Wei S, Zhou X, Qin Z, Jia J, Zhen X (2014) Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke. Brain Behav Immun 40:131–142

5. Jiang T, Yu JT, Zhu XC, Wang HF, Tan MS, Cao L, Zhang QQ, Gao L, Shi JQ, Zhang YD, Tan L (2014) Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy. Br J Pharmacol 171:3146–3157

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