Growth Hormone and Treatment Controversy; Long-Term Safety of rGH
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s40124-013-0009-5.pdf
Reference23 articles.
1. •• Carel JC, Ecosse E, Landier F, et al. Long-term mortality after recombinant growth hormone treatment for isolated growth hormone deficiency or childhood short stature: preliminary report of the French SAGhE study. J Clin Endocrinol Metab. 2012;97:416–25. This manuscript reports results from the European Union’s Safety and Appropriateness of GH treatment in Europe (EU SAGhE) study in France about the long-term mortality in GH-treated patients. This study found that persons treated with rGH were at an increased risk of death.
2. •• Savendahl L, Maes M, Albertsson-Wikland K, et al. Long-term mortality and causes of death in isolated GHD, ISS, and SGA patients treated with recombinant growth hormone during childhood in Belgium, The Netherlands, and Sweden: preliminary report of 3 countries participating in the EU SAGhE study. J Clin Endocrinol Metab. 2012;97:E213–7. This manuscript reports results from the European Union’s Safety and Appropriateness of GH treatment in Europe (EU SAGhE) study in Belgium, Sweden, and the Netherlands about the long-term mortality in GH-treated patients.
3. Katznelson L, Atkinson JL, Cook DM, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly—2011 update. Endocr Pract. 2011;17(Suppl 4):1–44.
4. Mestron A, Webb S, Astorga R, et al. Epidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Espanol de Acromegalia, REA). Eur J Endocrinol. 2004;151:439–46.
5. Holdaway IM, Bolland MJ, Gamble GD. A meta-analysis of the effect of lowering serum levels of GH and IGF-I on mortality in acromegaly. Eur J Endocrinol. 2008;159:89–95.
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