Relation between age and clearance rate of nine investigational anticancer drugs from phase I pharmacokinetic data

Author:

Borkowski Jane M.,Duerr Mary,Donehower Ross C.,Rowinsky Eric K.,Chen Tian-Ling,Ettinger David S.,Grochow Louise B.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference29 articles.

1. Brown TD, Donehower RC, Grochow LB, Rice AP, Ettinger DS (1987) A phase I study of menogaril in patients with advanced cancer. J Clin Oncol 5: 92

2. Balducci L, Parker P, Sexton W, Tantranond P (1989) Pharmacology of antineoplastic agents in the elderly patient. Semin Oncol 16: 76

3. Balducci L, Mowry K (1992) Pharmacology and organ toxicity of chemotherapy in older patients. Oncology 6: 62

4. Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16: 31

5. Dawling S, Crome P (1989) Clinical pharmacokinetic considerations in the elderly. Clin Pharmacokinet 17: 236

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