Design, synthesis, and molecular docking studies of new [1,2,4]triazolo[4,3-a]quinoxaline derivatives as potential A2B receptor antagonists-Reference-Cited by-同舟云学术

Design, synthesis, and molecular docking studies of new [1,2,4]triazolo[4,3-a]quinoxaline derivatives as potential A2B receptor antagonists

Published:2020-03-12 Issue:1 Volume:25 Page:291-306
ISSN:1381-1991
Container-title:Molecular Diversity
language:en
Short-container-title:Mol Divers

Author:

Ezzat Hany G.,Bayoumi Ashraf H.,Sherbiny Farag F.,El-Morsy Ahmed M.,Ghiaty Adel,Alswah Mohamed,Abulkhair Hamada S.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Link

http://link.springer.com/content/pdf/10.1007/s11030-020-10070-w.pdf

Reference28 articles.

1. El Maatougui A, Azuaje J, González-Gómez M et al (2016) Discovery of potent and highly selective A2B adenosine receptor antagonist chemotypes. J Med Chem 59:1967–1983. https://doi.org/10.1021/acs.jmedchem.5b01586

2. Moro S, Deflorian F, Bacilieri M, Spalluto G (2006) Ligand-based homology modeling as attractive tool to inspect GPCR Structural plasticity. Curr Pharm Des 12:2175–2185. https://doi.org/10.2174/138161206777585265

3. Basu S, Barawkar DA, Ramdas V et al (2017) A2B adenosine receptor antagonists: design, synthesis and biological evaluation of novel xanthine derivatives. Eur J Med Chem 127:986–996. https://doi.org/10.1016/j.ejmech.2016.11.007

4. Betti M, Catarzi D, Varano F et al (2018) The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2B receptor. Eur J Med Chem 150:127–139. https://doi.org/10.1016/j.ejmech.2018.02.081

5. Merighi S, Mirandola P, Varani K et al (2003) A glance at adenosine receptors: novel target for antitumor therapy. Pharmacol Ther 100:31–48

Cited by 35 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances on quinoxalines as target‐oriented chemotherapeutic anticancer agents through apoptosis;Archiv der Pharmazie;2024-05-31

2. Design, synthesis, and mechanistic insight of novel imidazolones as potential EGFR inhibitors and apoptosis inducers;Bioorganic Chemistry;2024-03

3. Novel Benzochromenes: Design, Synthesis, Cytotoxicity, Molecular Docking and Mechanistic Investigations;Future Medicinal Chemistry;2024-01

4. Rationale, in silico docking, ADMET profile, design, synthesis and cytotoxicity evaluations of phthalazine derivatives as VEGFR-2 inhibitors and apoptosis inducers;RSC Advances;2024

5. Molecular overlay-guided design of new CDK2 inhibitor thiazepinopurines: Synthesis, anticancer, and mechanistic investigations;Bioorganic Chemistry;2023-11