Molecular dynamics articulated multilevel virtual screening protocol to discover novel dual PPAR α/γ agonists for anti-diabetic and metabolic applications-Reference-Cited by-同舟云学术

Molecular dynamics articulated multilevel virtual screening protocol to discover novel dual PPAR α/γ agonists for anti-diabetic and metabolic applications

Published:2022-11-28 Issue: Volume: Page:
ISSN:1381-1991
Container-title:Molecular Diversity
language:en
Short-container-title:Mol Divers

Author:

Mandal Subhankar,Faizan Syed,Raghavendra Nulgumnalli Manjunathaiah,Kumar B. R. Prashantha^ORCID

Funder

DST Inspire India

Publisher

Springer Science and Business Media LLC

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Molecular Biology,General Medicine,Information Systems,Catalysis

Link

https://link.springer.com/content/pdf/10.1007/s11030-022-10571-w.pdf

Reference93 articles.

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2. Schulman IG (2010) Nuclear receptors as drug targets for metabolic disease. Adv Drug Deliv Rev 62(13):1307–1315. https://doi.org/10.1016/j.addr.2010.07.002

3. Swanson HI, Wada T, Xie W et al (2013) Role of nuclear receptors in lipid dysfunction and obesity-related diseases. Drug Metab Dispos 41(1):1–11. https://doi.org/10.1124/dmd.112.048694

4. Dixon ED, Nardo AD, Claudel T, Trauner M (2021) The role of lipid sensing nuclear receptors (PPARs and LXR) and metabolic lipases in obesity. Diabetes NAFLD Genes (Basel) 12(5):645. https://doi.org/10.3390/genes12050645

5. Zhang C, Zhang B, Zhang X et al (2020) Targeting orphan nuclear receptors NR4As for energy homeostasis and diabetes. Front Pharmacol 11:1–11. https://doi.org/10.3389/fphar.2020.587457

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