Effects of the periocular botulinum toxin on the ocular surface and anterior chamber: a prospective study in patients with hemifacial spasm and blepharospasm

Author:

Romero-Caballero María DoloresORCID,Miralles de Imperial-Ollero Juan AntonioORCID,Sarabia-Marín Elena,Villegas-Pérez María PazORCID

Abstract

Abstract Purpose To analyze using Pentacam®, the corneal and anterior chamber changes following periocular botulinum toxin injection in patients with facial dystonia. Methods Prospective study that included patients with facial dystonia that were going to receive a periocular botulinum toxin injection for the first time or six months or more after the previous injection. A Pentacam® examination was carried out in all patients before and 4 weeks after the injection. Results Thirty-one eyes were included. Twenty-two had a diagnosis of blepharospasm and nine of hemifacial spasm. Analysis of corneal and anterior chamber parameters revealed a significant decrease in iridocorneal angle after botulinum toxin injection (from 35 ± 10º to 33.8 ± 9.7º, p = 0.022). No other corneal or anterior chamber parameters changed significantly after the injection. Conclusions Periocular botulinum toxin injection causes narrowing of the iridocorneal angle.

Funder

Universidad de Murcia

Publisher

Springer Science and Business Media LLC

Subject

Ophthalmology

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